Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity related to bortezomib, a proteasome inhibitor Utilized in the remedy of numerous myeloma. Its synthesis or examine is important for guaranteeing the purity and security from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug used in the remedy of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-1): A important compound in the synthesis of imatinib, a drug that targets precise sorts of cancer, which includes Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for instance breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are generally intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their analyze is significant for optimizing the production course of action and ensuring higher purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is applied to treat breast cancer, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist used in the treatment method of breast most cancers. Numerous intermediates assist in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing 6-Piperidinedione with cancers which include ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the treatment method of colorectal most cancers and small cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, which have several purposes, including antiviral Qualities.
Vildagliptin Intermediates: Used in the manufacture of vildagliptin, an oral drug for style two diabetic issues that inhibits the enzyme DPP-4 to control blood sugar levels.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is involved with the synthesis of various gluconic acid derivatives, which can be used in foods, pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: A precursor 17b)-17-Acetyloxy-Estra-4-Ene- 7-(9-Bromononyl)-3-One while in the synthesis of canagliflozin, a medication utilized to manage form two diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).